Monday, September 12th, 2016
RESOWI Zentrum, Universitätsstrasse 15

08:00 - 13:30

Registration

09:45 - 10:15

ACIB and Biotechnology in Graz:
Highlights & current research and projects
Martin Trinker & Gabriele Berg

HS 15.02

10:15 - 10:30

Coffee Break 

10:30 - 12:30

Förderung der Grundlagenforschung in Österreich
Impulsreferate & Podiumsdiskussion

Begrüßung und Einleitung:
Josef Glößl, BOKU Wien und Vizepräsident der ÖGMBT

Teilnehmer:
Mag.in Barbara Weitgruber, Sektionschefin im BMWFW
Prof. Klement Tockner, Präsident des FWF
Prof. Oliver Vitouch, Präsident der UNIKO
Dr.in Henrietta Egerth, Geschäftsführerin der FFG
Prof.in Ellen Zechner, Vizepräsidentin des FWF
Prof. Lukas Huber, Vizepräsident der ÖGMBT

Moderation:
Mag. Andreas Schweiger, Pressesprecher der KFU Graz

 
HS 15.03

12:30 - 13:30

Lunch

13:00 - 14:15

Opening & Award Ceremony I - Research & PhD Awards

Günther Koraimann, Chair of the Organizing Committee
Caroline Schober-Trummler, Vice Rector Medical University of Graz
Birgit Strimitzer-Riedler, Land Steiermark representative
Angela Sessitsch, ÖGMBT President
Hermann Katinger, Polymun Scientific Preissponsor & Prof.em. BOKU
Rainer Englisch, THP Medical Products Preissponsor,

 
HS 15.03

14:15 - 14:30

Coffee Break

14:30 - 16:00

Lipid Metabolism, Disorders & Cancer I
Chairs: Martina Schweiger & Gerald Höfler

 
HS 15.03

14:30

Plenary Lecture - Jürgen Eckel (Düsseldorf, DE)
 The adipocyte - myocyte axis: A paradigm of organ crosstalk

15:00

Katharina Leithner
  PCK2 mediates glyceroneogenesis in lung cancer cells

15:10

Anne Rupprecht
  The mitochondrial uncoupling protein 2 abundance coincides with the metabolic adaptation in cancer cells

15:20

15:30

Andreas Prokesch
 The p53 pathway is activated by fasting in liver and controls macronutrient homeostasis
Plenary Lecture – Michael Lisanti (Manchester, UK)
 Common antibiotics target mitochondria and effectively eradicate cancer stem cells, across multiple tumor types

16:00 - 16:30

Coffee Break

16:30 - 18:00

Ageing and Neurodegeneration
supported by BioTechMed-Graz
Chairs: Tobias Eisenberg & Frank Madeo

 

HS 15.03

16:30

Plenary Lecture - Bence Racz (Budapest, HU)
  You are what you eat: Influence of nutrition on hippocampal synaptic plasticity

17:00

Thomas Birngruber
  A new focal glioblastoma model with a cerebral open-flow microperfusion (cOFM) as a permanent fluidic interface

17:10

Julia Ring
  Cytosolic Abeta targets mitochondria inducing cell death in a yeast model of Alzheimer's diseases

17:20

Michael Moschinger
  Investigation into gender-specific expression of important mitochondrial proteins in mice

17:30

17:40

BioTechMed-Graz Lecture  
Rudolf Zechner - Introduction to BioTechMed-Graz
Satchin Panda (La Jolla, US) - Time-restricted feeding for increasing healthy lifespan

18:10 - 19:00

Wine & Science

 
Foyer & SR 1-4

19:00 - 22:00

Poster Session I

SR 1-4

Tuesday, September 13th, 2016

08:00 - 13:30

Registration

09:00 - 09:30

FEBS National Lecture - Alan Warren (Cambridge, UK)
  Linking leukaemia to the quality control of ribosome assembly

 
HS15.03

09:40 -10:40

Concurrent sessions HS15.03 & HS15.02 until 12:30

Enzymes and Nanomachines 
Chairs: Helmut Bergler & Peter Macheroux & Brigitte Pertschy

HS15.03

09:40

Plenary Speaker - Tim Clausen (Vienna, AT)
  Linking protein phosphorylation and degradation: How a specific phospho-signal serves as a degradation tag

10:10

Tea Pavkov-Keller
  The self-assembly of SbsC, the S-layer protein from Geobacillus stearothermophilus

10:20

Geoffrey Gourinchas
  Elucidating the longe-range signal transduction in red-light activated diguanylyl cyclases

10:30

Lisa Kappel
  Degradation of the biopolymer chitin and its monomeric subunit N-acetylglucosamine in fungi is regulated by the novel NDT80-like transcription factor RON1

09:40 - 10:40

Translational Oncology I: "From Basics... "
Chairs: Emilio Casanova & Robert Eferl

HS15.02

09:40

Plenary Speaker - Erwin Wagner (Madrid, SP)
  Inflammation-associated liver cancer and the systemic effects of cancer cachexia

10:10

Monira Awad
  The role of the protocadherin CDHR5 (Mucdhl) in colorectal cancer

10:20

Christine Pirker
  Genome-wide characterization of malignant pleural mesothelioma cells: TERT promoter mutations are associated with the sarcomatoid subtype

10:30

Nicole Prutsch
  The TYK2-STAT1 pathway in aggressive T-cell lymphoma: A new therapeutic intervention site?

10:40 - 11:00

Coffee Break

11:00 - 12:30

Secretion Systems
Chairs: Ellen Zechner & Günther Koraimann

HS 15.03

11:00

Plenary Speaker - Elisabeth Grohmann (Berlin, DE)
  Key players of an Enterococcus type IV secretion system

11:30

Verena Kohler
  Polycistronic expression and structural characterization of a
Gram-positive type IV secretion system in Bacillus megaterium

11:40

Christian Gruber
  Conjugative DNA transfer is enhanced by plasmid R1 partitioning proteins

11:50

Dina Vorkapic
  An O-linked protein glycosylation system modulates biofilm development in Vibrio cholerae by affecting the secretion of biofilm matrix proteins

12:00

Plenary Speaker - Gabriel Waksman (London, UK)
  Structural and molecular biology of bacterial secretion systems

11:00 - 12:30

Translational Oncology I: "From Basics..."
Chairs: Emilio Casanova & Robert Eferl

HS15.02

11:00

Plenary Speaker - Andreas Villunger (Innsbruck, AT)
  The PIDDosome in cell death and cell cylce control

11:30

Elisabeth Glitzner
  Molecular characterization of the EGF receptor (EGFR) in endothelial cells

11:40

Carina Dinhof
  YK-4-279, a novel small molecule Ets-inhibitor, induces mitotic arrest in human Ewing's sarcoma and melanoma cell models

11:50

Sabine Lagger
  PDGFRB modulates DNA integrity in anaplastic large cell lymphoma

12:00

Elisa Redl
  Oncogenic signaling and epigenetic deregulation – the function of DNMT1 in NPM-ALK driven lymphomagenesis

12:10

Alexandra Zisser
  HDAC1 genetic deletion accelerates NPM-ALK+ lymphoma formation by activating anti-apoptotic protein expression

12:20

David Pereyra 
Liver regeneration is impaired in mice suffering from Alpha-Granule Deficiency

12:30 - 13:30

Lunch Break & Switch to Poster Sesssion II

13:30 - 14:30

ÖGMBT General Assembly

HS15.02

14:30 - 16:00

Infectious Diseases and Novel Treatments
Chairs: Karl Lohner & Christoph Högenauer & Joachim Reidl

 

HS15.03

14:30

Plenary Speaker - Christoph Högenauer (Graz, AT)
  Fecal microbiota transplantation – A prototype for new therapeutic concept!

15:00

Matthias Tonner
  The labile iron pool in Leishmania

15:10

Fatih Cakar
  Identification and characterization of in vivo repressed genes in Vibrio cholerae by using a novel version of a recombinase-based reporter system

15:20

Nermina Malanovic
  Peptide oligomerization as a determinant factor of antibacterial activity

15:30

Plenary Speaker - Bob Hancock (Vancouver, CA)
  Alternative strategies for antibiotic resistant infections

14:30 - 15:30

Applying correctly – but how?
Career Lecture with Birgit Leitner (Employer Brand Manager ERBER Group)

 
HS15.02

15:30 – 16:15

High throughput, scaleable, and reusable ion exchange membrane chromatogrphy
Workshop with Wolfgang Weinkum (PALL Austria)

PALL booth / foyer

16:00 - 16:30

Coffee Break

16:30 - 18:00

Young Scientists Austria
Chairs: Vinay Sachdev & Pablo Vieyra Garcia

 


HS15.03

16:30

Katrin Unterhauser (DK Enzymology)
  Short overview of the DK Enzymology
  Enterotoxin tilivalline is a mitotic poison that stabilizes microtubules

16:45

Katharina Pressler
  AAA+ proteases and their role in distinct stages of the Vibrio cholerae lifecycle

16:55

Corina Madreiter-Sokolowski (DK-MCD)
  Short overview of the DK Metabolic and Cardiovascular Disease
  Cancer-specific mitochondrial calcium homeostasis may offer new treatment strategies

17:10

Wael Al Zoughbi
  A tumor suppressor function for ATGL: The director's cut

17:20

Izabela Borek (DK-MOLIN)
Short overview of the DK Molecular Fundamentals of Inflammation 
Bone Morphogenic Protein 7 (BMP7) promotes in vitro generation of high numbers of inflammatory Langerhans-like dendritic cells

17:35

Corinna Krump
  Repression of monocyte lineage identity is required for Langerhans cell differentiation but not for alternative DC fates

17:45

ÖGMBT Young Life Scientists Austria - YLSA
Jonas Ramoni & Pascal Mülner
Kick-off info event Graz

 
HS15.03

18:00 - 19:00

Dinner

 
Foyer

19:00 - 21:00

Poster Session II

 
SR1-4

from 21:00

Funk´n Rock with MurBeat

Wednesday, September 14th, 2016

08:00 - 13:30

Registration

09:00 - 10:30

Microbiota Today
Chairs: Gabriele Berg & Christine Moissl-Eichinger & Christoph Sensen

 
HS15.03

09:00

Plenary Speaker - David Berry (Vienna, AT)
  Insights into gut microbiota function using single cell isotope probing

09:30

Kaisa Koskinen
  The correspondence of nasal microbiome and normal olfactory function

09:40

Kathrin Lippert
  Composition and functions of the gut microbiota and associations with obesity and the metabolic syndrome in seniors

09:50

Birgit Mitter
  Transcriptome profiling of the endophyte Burkholderia phytofirmans PsJN indicates sensing the drought stress of the host plant

10:00

Plenary Speaker - John van der Oost (Wageningen, NL)
  Discovery of new CRISPR systems

09:00 - 10:30

Biophysics Austria Annual Meeting
Chair: Peter Pohl

HS15.02

09:00

Peter Pohl
  Gating of the protein translocation complex (SecYEG)
expressing HEK293 cells

09:30

Niroj Shrestha
  Trimeric intracellular cation channel (TRIC-A) regulates Ca2+ cycling in RYR2

09:50

Barbara Eicher
  Joint SAXS/SANS data analysis of membranes exhibiting lipid asymmetry

10:10

Inmaculada Sanchez Romero
  Designer Optical Neurotransmitter Sensors (DOTS)

10:30 - 11:00

 
Coffee Break

11:00 - 12:30

Systems and Synthetic Biology
Chairs: Kai Uwe Fröhlich & Helmut Schwab

 
HS15.03

11:00

Plenary Speaker – Călin Guet (Klosterneuburg, AT)
  What Synthetic Biology teaches us about Biology

11:30

Michael Traxlmayr
  A hyperstable miniprotein as an alternative to antibodies

11:40

Bernd Albrecht
  Scaffolding for metabolic engineering endeavors

11:50

Stephanie Kainrath
  An optogenetic FGFR1 variant inhibited by green light illumination

12:00-12:30

12:00

12:10

12:20

Lipid Metabolism, Disorders & Cancer II
Chairs: Martina Schweiger & Gerald Höfler

Melanie Korbelius
Consequences of defective lipolysis in the small intestine on lipid metabolism 
Furkan Alkan
Knockdown of a metabolic gene is reducing the proliferation while increasing metastasis of cancer cells
Cedric De Smet
A novel lipid sensor and adipogenesis regulator in the endosomal membrane

HS15.03

11:00 - 12:30

Biophysics Austria Annual Meeting
Chair: Peter Pohl

HS15.02

11:00

Invited Speaker: Andreas Horner
  H-bond formation governs the unitary water permeability of narrow channels

11:30

Gabriel Macher
  Inhibition of proton transport in UCP1 and 3 – a closer look

11:50

Christoph Enz - Fa. Cenibra (sponsored talk)
  Molecular forces, biomembranes, and how the former can be measured on the latter

12:10

Gerhard Schütz
  Label density variation to probe membrane protein nanoclusters in  STORM/PALM-based superresolution microscopy

12:30 - 13:30

Lunch Break 

13:30 - 15:30

Biophysics Austria Annual Meeting - Poster Session III

 
SR3

13:30 - 15:30

Translational Oncology I: "... to Translational" 
Chairs: Michael Bergmann & Lukas Kenner

 
HS15.03

13:30

Plenary Speaker -  Pernille Hojmann (Kopenhagen, DK)
  Exercise protects from cancer by regulation of immune function

14:00

Pablo Vieyra-Garcia
  Understanding benign T-cell infiltration in mycosis fungoides: Malignant clones are not alone

14:10

Jasmin Svinka
  STAT1 promotes immune escape of intestinal cancer

14:20

Monika Sachet
  In vitro activation of tumor-infiltrating leukocytes from surgical specimens

14:30

Florian Rüker
  Domain-exchanged antibody with potentiated effector functions

14:40

Martha Gschwandtner
  Translating research into therapy: Targeting the chemokine-glycosaminoglycan interaction as novel approach for interfering with cancer metastasis

14:50

Philipp Staber
  EXALT: Extended analysis for leukemia/lymphoma treatment

15:00

Anna Obenauf
  Unintended consequences of targeted cancer therapy: Therapy induced tumor secretomes fuel drug resistance and tumor progression

15:10

Taraneh Beikbaghban
  Interplay between EGFR and MET gene amplifications upon receptor tyrosine kinase (RTK) inhibitor selection

15:20

Diana Groza
  Uptake kinetics of a platinum(IV) bismaleimide complex in vitro and in vivo

15:30 - 16:00

Coffee Break & Exhibitor Quiz Prizes I

16:00 - 17:30

Single Molecules and Membranes 
Chairs: Klaus Groschner & Sepp Kohlwein

HS15.03

16:00

Plenary Speaker - Jennifer Lippincott-Schwartz (Bethesda, US)
supported by NAWI Graz
  Windows into cell metabolism through imaging

16:30

Emrah Eroglu
  Development of novel FP-based probes for live-cell imaging of nitric oxide dynamics

16:40

Oleksandra Tiapko
  Photopharmacological modulation of TRPC3/6 as a strategy to govern neuronal excitability

16:50

Simona Migliano
  The role of Vps4 on endosomes during the last seconds of intraluminal vesicle biogenesis

17:00

Plenary Speaker - Dirk Trauner (Munich, DE)
  Controlling Biological Function With Photopharmacology

16:00 - 17:20

Translational Oncology II: "... to Translational"
Chairs: Martin Pichler & Armin Gerger

HS15.02

16:00

Plenary Speaker - Cornelia Ulrich (Utah, US)
 Advancing precision prevention and translational oncology through metabolomics strategies

16:30

Regina Soldo
  Cross-platform reproducibility and quality control for improving multiplex tumor-autoantibody testing

16:40

Verena Stiegelbauer
  MicroRNA196 regulates metastases formation in colorectal cancer

16:50

Sarah Kammerer
  KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients

17:00

Johannes Laengle
  Oncolytic influenza A virus expressing interleukin-15 diminishes tumor growth in vivo

17:10

Gerald Prager
  Implementation of a screening program for mismatch-repair deficient(MMR)-colon cancer for identifying patients eligible to immunotherapy with programmed death 1(PD1)-immune checkpoint inhibitor Pembrolizumab

17:30 - 18:00

Exhibitor Quiz Prizes II & Award Ceremony II - Best Talk & Best Poster

 
HS15.03

18:00

Closing Remarks

 
HS15.03